Persons familiar with the common watermelon vine need no description of the plant which produces colocynth apples. Citrullus colocynthis supplement health benefits, dosage. How bitter apple is effective for various diseases is listed in repertory format. Enhancement of callus induction and cucurbitacin content in. Colocynth, citrullus colocynthis, hairystemmed perennial vine of the gourd family cucurbitaceae, native to the mediterranean region. Medicinal uses of different parts of citrullus colocynthis. A qualitative analysis was performed for the identification of the presence. Colocynth is used on the skin for nerve pain in people with diabetes.
Citrullus colocynthis fruits were also traditionally used as an abortifacient and to treat constipation, oedema, bacterial infections, cancer and diabetes 47. Uses dried pulp of unripe fruit is used medicinally for its drastic purgative and hydragogue cathartic action on the intestinal tract. The seeds of colocynth, which must be heated to remove their bitter bioactive. The plant has small, pale greenish yellow flowers, forked tendrils, and. Colocynthishomaccord injection solution is a clear, colorless solution. However therapeutic applications and adverse effects of c. The present study reveals the medicinal uses, chemical compositions and examines recent investigations on the therapeutic activities of extracts and chemicals identified from citrullus colocynthis. Citrullus colocynthis famine foods purdue university. Citrullus colocynthis is a very droughttolerant medicinal species, closely related to watermelon c.
Herbal medicinal importance of citrullus lanatus mentioned in. Effects of alkaloid rich extract of citrullus colocynthis fruits on artemia salina and human cancerous mcf7 and hepg2 cells aniruddha mukherjee, savita d patil abstract in the present research the anticancer effect of alkaloid rich extract of citrullus colocynthis fruits was investigated. This powder is so inflammable that the arabs collect it to use as kindling. Indeed, if you will imagine a watermelon vine bearing a small, hard fruit with a bitter pulp, you. The present study aimed to investigate the antiobesity effect. C have been used traditionally in the treatment of diabetes mellitus. These pains may be accompanied by a backache and may even cause some sort of numbness at certain points. Introduction the use of plants for medicinal purposes has been.
Citrullus colocynthis, commonly known as the colocynth, bitter apple, bitter cucumber. We, for the first time, conducted this quantitative study in the area to document medicinal plants uses, to preserve traditional knowledge, and also to motivate the local residents against the vanishing wealth of traditional knowledge of medicinal flora. Citrullus colocynthis an overview sciencedirect topics. Pdf the present study reveals the medicinal uses, chemical compositions and examines recent investigations on the therapeutic activities of. Citrullus colocynthis 2 growth its fruit, which is lemonsized, yellowish, greenmottled, spongy, and extremely bitter, is a powerful hepatic stimulant and hydragogue cathartic. The present study aimed to investigate the antiobesity effect of the ethanol extract of colocynth flesh fcee in 3t3l1. This is a dangerously powerful plant that has been found to work as a medicine in ayurveda as well as homeopathy. Colocynth citrullus colocynthis uses, dosage, side effects. It is also used in combination products for treating liver and gallbladder ailments. Synonym cucumis colocynthis, citrullus colocynthis l.
Citrullus colocynthis has a number of interesting names like indrayan hindi, bitter apple, vine of sodom, and desert gourd. Provided by ars systematic botany and mycology laboratory. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter. Despite serious safety concerns, colocynth is used for diabetes, high cholesterol and blood fats called triglycerides, constipation, and tuberculosis. The folk knowledge of medicinal plants species of kohesafaid range was unexplored. The article also presents some of the functions of the chemicals present and attempt to emphasize and create an awareness of the great potential of citrullus colocynthis as a source of novel. The current work investigates the effects of pulp and seed extract of c. Citrullus colocynthis famine foods plants that are not normally considered as crops are consumed in times of famine purdue university, west lafayette, indiana. Jonathan hardy discusses two patients treated with medicines in the cucumber family in recent years we have developed our homeopathic understanding of remedies in groups and families.
In order to document the traditional uses of citrullus colocynthis survey was carried out during the. A qualitative analysis was performed for the identification of. Anticandidal screening and antibacterial of citrullus. The second edition of an excellent guide to the edible uses of plants, though it does not give any details of cultivation etc.
Journal of medicinal plants studies ethnobotanical studies of. Medicinal action and uses it is a powerful drastic hydragogue cathartic producing, when given in large doses, violent griping with, sometimes, bloody discharges and dangerous inflammation of the bowels. Egusi seed is botanically known as citrullus colocynthis curcurbita citrullus l. Other side effects include convulsions, paralysis, and death. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while. The fruits are recognized for their wide range of medicinal uses and promising pharmaceutical potential. Phenolic compounds and antiradical properties of methanolic extracts of citrullus colocynthis and plantago major in iran afsaneh moslemi mehni 1, fatemeh shahdadi 2 1young researchers and elite club, jiroft branch, islamic azad university, jiroft, iran 2department of. Death has resulted from a dose of 1 12 teaspoonsful of the powder. Citrulluscolocynthis bitterapple and spelling variants redirect here.
Colocynth indravaruni, bitter apple is a great herbal plant with many useful properties. This study was carried out in human breast cancer cell growth. Colocynthis tends to be the most beneficial as a homeopathic remedy for those who have suppressed anger. There have been reports of death following ingestion of just 112. Citrullus colocynthis, an israeli desert plant, as a. Effects of alkaloid rich extract of citrullus colocynthis fruits on artemia salina and human cancerous mcf7 and hepg2 cells aniruddha mukherjee, savita d patil abstract in the present research the anticancer effect of alkaloid rich extract of citrullus colocynthis fruits. Citrullus colocynthis is a medicinal plant that has anticancer property mediated by apoptosis. Quantitative study of medicinal plants used by the.
Names of bitter apple in various languages of the world are also given. Citrullus colocynthis contained carbohydrate, protein, separated amino acid, tannins, saponins. Representation of different chemical constituents found in various plant parts extracts of citrullus colocynthis l. Issn phytochemical analysis of a folklore medicinal plant. Medicinal the dried, unripe fruit pulp constitutes the drug colocynth, which is a very strong laxative. It was banned by the food and drug administration in 1991 taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. The colocynth grows in sandy, coastal, or desert soils and commonly spreads vegetatively. Citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. The present study aimed to investigate the antiobesity effect of the ethanol extract of colocynth flesh fcee in 3t3l1 cells following treatment at different doses.
The main clinical feature was acute rectorrhagia preceeded by mucosal diarrhea with tenesmus, which gradually progressed to bloody diarrhea and overt rectorrhagia within 3 to 4 hours. Jan 15, 2018 colocynth indravaruni, bitter apple is a great herbal plant with many useful properties. Schrad is a valuable cucurbit plant, widely distributed in the desert areas of the world. Bitter apple herb uses, benefits, cures, side effects, nutrients.
Herbal medicinal importance of citrullus lanatus mentioned. Citrullus colocynthis at encyclopedia of life citrullus colocynthis at national center for biotechnology information. Phytochemical analysis of a folklore medicinal plant citrullus colocynthis l bitter apple c. Science and technology, general agricultural chemicals antimitotic agents antineoplastic agents fertilizers research food additives germination liquid chromatography phytochemicals plant. Citrullus colocynthis fruits are usually recognized for its wide range of medicinal uses as well as pharmaceutical and nutraceutical potential. Current situation of micronutrient deficiencies in west africa pdf. Its botanical name is citrullus colocynthis and it belongs to cucurbitacae family. Phenolic compounds and antiradical properties of methanolic. It was known in biblical times as a source of seed oil and its fruits were used as an efficient laxative. Citrullus colocynthis fruits are usually recognized for its wide received in revised form range of medicinal uses as well as pharmaceutical and nutraceutical. Dec 31, 2014 medicinal herbs such as citrullus colocynthis c. Citrullus colocynthis, a member of the cucurbitaceae family, is widely distributed in north africa. It was always known as a toxic gourd but was turned to as a food in desperate times. There have been reports of death following ingestion of just.
Report by journal of the alabama academy of science. The benefits, dosage and side effects of citrullus colocynthis. Thisisalsousedforthepoisonoussoda apple,aspeciesofnightshade. Citrullus colocynthis on integrated taxonomic information system. Citrullus colocynthis as the cause of acute rectorrhagia. Pdf medicinal utility of melon citrullus colocynthis l. Citrullus colocynthis bitter apple ayurvedic properties. Enhancement of callus induction and cucurbitacin content in citrullus colocynthis l. Citrullus colocynthis, with many common names including colocynth, bitter apple, bitter cucumber, desert gourd, citation needed egusi, vine of sodom, or wild gourd, is a desert viny plant native to the mediterranean basin and asia, especially turkey especially in regions such as izmir, and nubia. Colocynth citrullus colocynthis flesh extract suppresses. Citrullus colocynthis schrad, aqueous extract, acetone extract, antibacterial, anticandidal, iran. Four patients with colocynth intoxication are presented. Phenolic compounds and antiradical properties of methanolic extracts of citrullus colocynthis and plantago major in iran afsaneh moslemi mehni 1, fatemeh shahdadi 2 1young researchers and elite club, jiroft branch, islamic azad university, jiroft, iran 2department of food engineering, jiroft university, iran key words. C and its natural variants are not determined well.
May 10, 2010 colocynthis works well for sharp pains down the outer side of the thigh, leg, or foot. When the fruit is ripe its pulp dries to form a powder used as a bitter medicine and drastic purgative. We have found, for example, that remedies which come from the same family of plants all share a number of characteristics. The folk medicinal use as a broadspectrum antimicrobial agent is validated.
Enhancement of callus induction and cucurbitacin content. Effects of alkaloid rich extract of citrullus colocynthis. Colocynthis, bitter apple, bitter cucumber, colocynth. Uses, benefits, cures, side effects, nutrients in bitter apple. Bitter apple herb uses, benefits, cures, side effects. Colocynthis homaccord fda prescribing information, side. Chemical constituents and pharmacological effects of. Citrullus colocynthis 2 growth its fruit, which is lemonsized, yellowish, greenmottled, spongy, and extremely bitter, is a. Sekar abstract phytochemical screening of citrullus colocynthis belonging to the family cucurbitaceae was carried out for finding its medicinal values. An other medicinal use of this plant declared by herbal medicine. Jun 14, 2018 citrullus colocynthis, also known as bitter cucumber, is a fruitbearing plant sometimes used medicinally citrullus colocynthis is used to treat diabetes, since it may be able to induce insulin secretion from the pancreas after supplementation, while reducing blood glucose and improving lipid levels. It was banned by the food and drug administration fda in 1991. Taking even very small amounts of colocynth can cause severe irritation of the stomach and intestine lining, bloody diarrhea, kidney damage, bloody urine, and inability to urinate. This plant tends to control kapha and pitta doshas.
Based on the above findings, the researchers agreed that citrullus colocynthis is suitable for use as an antiinflammatory agent. Nov 19, 2017 citrullus colocynthis has a number of interesting names like indrayan hindi, bitter apple, vine of sodom, and desert gourd. The effect of pulp and seed extract of citrullus colocynthis. Colocynthis citrullus, but is now classified as citrullus colocynthis. It is known by various names such as bitter cucumber, pumpkin seeds, egusi melon, vine of sodom plant, wild gourd, bitter apple, colocynth or desert gourd. Chemical constituents and pharmacological effects of citrullus. Origin native asia, mediteranean region, tropical africa. Herbal medicinal importance of citrullus lanatus mentioned in the ahadith. Medicinal action and usesit is a powerful drastic hydragogue cathartic producing, when given in large doses, violent griping with, sometimes, bloody discharges and dangerous inflammation of the bowels.
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